Response to Supplement and Placebo in GERD

Exclusion Criteria

• •Individuals taking a proton pump inhibitor (PPI) or H2 receptor blocker with a dose change within 2 weeks of the initial study visit.
• •Individuals with Crohns disease, systemic sclerosis, known active ulcer disease, gastric cancer, Barrett's esophagitis
• •Significant pain or difficulty with swallowing
• •Heavy alcohol use (defined by \> 6 drinks/week for women and \> 13 drinks/week for men)
• •Concurrent pregnancy
• •Dementia
• •Uncontrolled psychiatric disease
• •Individuals unable to complete a paper symptom diary for 6 of 7 days prior to their baseline visit
• •Subjects whose symptoms are predominantly dyspeptic more than heartburn or reflux
• •Subjects who have used homeopathy for GI symptoms or have received constitutional homeopathic treatment within the past 2 weeks
• •Subjects taking herbal products or other supplements for GERD or dyspepsia related symptoms (includes peppermint oil)
• •Subjects who have taken \> 12 doses of NSAIDS within the prior 30 days (aspirin ≤ 325 mg daily is allowed)
• •Subjects with lactose intolerance