Fecal Microbiota Transplantation for C Diff Infection

Inclusion Criteria

• •1. Subject is at least 18 years old.
• •2. Subject has recurrent or relapsing CDI defined as:
• •* At least three episodes of mild-to-moderate CDI and failure of a 6-8 week taper with vancomycin with or without an alternative antibiotic (e.g., rifaximin, nitazoxanide, fidaxomicin). OR
• •* At least two episodes of severe CDI resulting in hospitalization and associated with significant morbidity. OR
• •* Moderate CDI not responding to standard therapy (vancomycin) for at least a week. OR
• •* Severe C. difficile infection with toxic megacolon, not responding to standard therapy or the use of IVIg.
• •3. Subject is willing and able to provide informed consent.
• •4. If a female of childbearing potential, subject has agreed to use an acceptable form of birth control for up to 4 weeks after FMT treatment.