Effect of the DPP-4 Inhibitor Sitagliptin on Islet Function After Mixed Meal in Patients With Type 2 Diabetes

Exclusion Criteria

• •Liver disease or ALAT three times above upper reference range
• •Diabetic nephropathy (GFR \< 50 mL/min/1.73 m2 or albuminuria)
• •Proliferative diabetic retinopathy
• •Treatment with any glucose-lowering medication except metformin
• •Previous myocardial infarction, coronary heart disease or insatiable angina pectoris in the last 6 months.
• •Previous surgery on the gastrointestinal tract
• •Larger surgical intervention during the last 12 weeks
• •Treatment with oral steroids or thiazide diuretics
• •Treatment with digoxin
• •Smokers
• •Participation in another study the last 4 weeks
• •Paracetamol intolerance