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Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma | Clinical Trials | Clareo Health

TERMINATEDPHASE2

Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma

NCT01897792•University of Alabama at Birmingham

View on ClinicalTrials.gov

Summary

The purpose of this study is to determine the effect of antioxidant vitamins (vitamins C and E) on the development of coagulation derangements and nosocomial pneumonia after severe trauma in patients.

Eligibility

Age

19 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Adult trauma patients admitted to the emergency department at the University of Alabama at Birmingham (UAB) Hospital
•Blunt or penetrating injury
•UAB highest trauma activation

Exclusion Criteria

•Age \< 19 years of age
•Patients with known bleeding diathesis or who are concurrently taking anticoagulant medication
•Patients with known liver disease
•Minor patients
•Pregnant patients (known or suspected pregnancy)
•Patients who are incarcerated
•Patients who lack a surrogate

Locations (1)

The University of Alabama at Birmingham Hospital

Birmingham, Alabama, United States

Key Dates

Start Date

May 1, 2013

Primary Completion Date

February 1, 2015

Completion Date

February 1, 2015

Last Updated

March 29, 2017

Enrollment

ACTUAL participants

Conditions

CoagulopathyNosocomial Pneumonia

Interventions

Vitamin C

DIETARY_SUPPLEMENT

Vitamin E

DIETARY_SUPPLEMENT

Saline (for Vitamin C)

DIETARY_SUPPLEMENT

Placebo (for Vitamin E)

DRUG

Point of Care Fibrinogen Measurement in Trauma Patients in the Emergency Department

NCT07097337

Trauma Induced CoagulopathyTrauma Coagulopathy+4 more

View study

RECRUITING

Assessment of Artificial Intelligence Algorithms for ROTEM

NCT07043556

Coagulopathy

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COMPLETED

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 29, 2017Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma

Inclusion Criteria

Exclusion Criteria

Point of Care Fibrinogen Measurement in Trauma Patients in the Emergency Department

Assessment of Artificial Intelligence Algorithms for ROTEM

Microcirculation and Coagulopathy in Sepsis

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