Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Poznan University of Medical Sciences
Age
18–60
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
age \> 18 years \<60 years,
duration of diabetes \>3 years,
lack of metabolic control- HbA1C\>7,5% (despite participation in 5-day WHO education program)
treated with intensive insulin therapy
You may not be if
metabolically decompensate diabetes with acetonuria,
suspected lack of compliance,
lack of glucose and ketones self-monitoring,
hypoglycaemic unawareness or recurrent severe hypoglycemia (defined as more than two episodes of hypoglycemia lowered than 60 mg/dl with loss of consciousness, required assistance to treat) in the past 3 months,
recurrent diabetic ketoacidosis (more than two episodes in the past year)
another serious medical illness,
pregnancy or sexually active woman unwilling to take birth control.
renal impairment (estimated on the value calculated glomerular filtration rate using the MDRD formula-estimated glomerular filtration rate, eGFR\<45 mL / min
liver cell damage Alanine aminotransferase (ALT), Aspartate aminotransferase (AST) greater than twice the upper normal limit),
history of drug or alcohol abuse or those who used this drug before
changes in the way of antihypertensive and antihyperlipemic treatment.
Clareo Health | Metformin Therapy in Type 1 Diabetes Mellitus.
