Immune Resolution After Staphylococcus Aureus Bacteremia

Inclusion Criteria

• •At least one blood culture positive for S. aureus
• •Patients aged ≥18 years
• •At least two of four systemic inflammatory response syndrome (SIRS) criteria on the day of positive blood cultures. SIRS criteria are:
• •* Body temperature less than 36°C(96.8°F) or greater than 38°C(100.4°F)
• •* Heart rate greater than 90 beats per minute
• •* Tachypnea (high respiratory rate), with greater than 20 breaths per minute; or, an arterial partial pressure of carbon dioxide less than 32 mmHg
• •* WBC less than 4000 cells/mm³ (4 x 109 cells/L) or greater than 12,000 cells/mm³ (12 x 109 cells/L); or the presence of greater than 10% immature neutrophils (band forms)