Age

18–85

Sex

ALL

Healthy volunteers

Not accepted

Uncontrolled hypertension (defined as SBP ≥ 140 mmHg during 24Hr Ambulatory BP monitoring)
Current treatment with ≥ 3 anti-hypertensive drugs (including at least one diuretic)
Renal artery diameter ≥5mm by digital angiography
Accessibility of renal vasculature

Estimated GFR \< 45
Type 1 Diabetes
Known renovascular abnormalities (eg, renal artery stenosis, previous renal artery stenting or angioplasty)

Feasibility Study of Renal Denervation for the Treatment of Resistant Hypertension