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Multidisciplinary Approach Versus Conventional Approach in Colonic Preparation of Hospitalized Patients. A Randomized Controlled Trial
Colonoscopy is the gold standard diagnostic procedure for colonic disease. Excellent bowel cleansing is critical for this procedure. However, an inadequate bowel cleansing is a common problem that occurs up to 20% of procedures. This fact has a deep clinical and economical impact. In fact, inadequate bowel preparation is associated to misdiagnosis in 30% of lesions. Moreover several clinical conditions such as cirrhosis, antidepressant drugs, and hospitalized patients are predictive factors of inadequate colonic preparations. These circumstances have promoted multiple clinical trials, however there is no consensus about the optimal strategy for colonic cleansing. Education in colonic preparation has obtained conflicting results. Polyethylene glycol (PEG) and sodium phosphate solutions have been the commonest preparations used with a similar efficacy. However, the large volume to ingest (4 litters) makes PEG compliance difficult. Likewise, sodium phosphate also contains high levels in sodium and phosphate which contraindicate its use in elderly patients and / or with comorbidity. The use of adjuvants such as olive oil and bisacodyl allows reducing the volume of polyethylene glycol thereby improving the tolerance and right colon preparation. The aim of this study is to compare the efficacy of a multidisciplinary approach (education, fiber free diet, polyethylene glycol (PEG) 2L, and adjuvant bisacodyl + olive oil) vs. a conventional approach (fiber free diet+ PEG 4L in split doses ) in cleaning the colon of hospitalized patients.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Hospital de Sabadell
Sabadell, Barcelona, Spain
Start Date
May 1, 2013
Primary Completion Date
December 1, 2013
Completion Date
December 1, 2013
Last Updated
May 15, 2013
162
ESTIMATED participants
Education
BEHAVIORAL
Fiber free diet
OTHER
Adjuvants
DIETARY_SUPPLEMENT
Polyethylene glycol (PEG)
DRUG
Bisacodyl
DRUG
Lead Sponsor
Corporacion Parc Tauli
NCT07127354
NCT02781493
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT01929590