Effect of Memantine Oral Pump on Language in Patients With Probable Alzheimer's Disease

Exclusion Criteria

• •involved in another clinical trial within 4 weeks prior to screening
• •severe or unstable disease: acute or severe asthma, unstable or severe cardiovascular disease, acute peptic ulcer,chronic renal failure
• •bradycardia (pulse rate less than 50bpm), sick sinus syndrome
• •any laboratory finding including cognitive impairments(vitamine B12 or folic acid, syphilis, thyroid disease)
• •severe auditory or visual disturbance
• •other degenerative disease or psychosis
• •taken any drug used for the treatment of Alzheimer's disease or dementia