Randomized, Double-blind, Two Arms, Multicenter, Phase III Study of Berinert for Treatment of ACE Induced Angioedema

Exclusion Criteria

• •Diagnosis of angioedema of other genesis: e.g. hereditary angioedema, C1-inhibitor deficiency, allergic edema, anaphylaxis, insect bite, trauma, abscess, local inflammation, local tumour, post-operative or post-radiogenic edema, salivary gland disorders
• •Participation in a clinical study in the past 30 days
• •Patients with simultaneous itchiness of skin (acute urticaria)
• •Patients with a history of angioedema before taking ACEi
• •History of hypersensitivity to any of the study drugs or medicine with a similar chemical structure.
• •Pregnancy and/or breastfeeding
• •Mental retardation of the patient with restriction of general judgment and awareness
• •History of drug abuse (including alcohol and alcoholic liver disorders)
• •Potentially unreliable patients
• •Patients who are not suitable for the study in the opinion of the investigator