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A Randomized Controlled Clinical Trial of Regenerative Protocols to Treat Immature Necrotic Teeth
Both methods tested in this study disinfect the non-vital root canals and induce blood clot formation inside the root canal. One method places calcium hydroxide inside the root canal after disinfection and the blood clot is induced four weeks later. The other method performs disinfection and induction of blood clot in one appointment. The investigators hypothesize that both methods will obtain the same success rate in eliminating infection, increase in root length and canal walls thickness.
Collagen is placed on top of the blood clot, followed by white MTA. Glass ionomer is used to seal the access to the canal, which will be replaced by a permanent restoration 3 months later.
Age
6 - 25 years
Sex
ALL
Healthy Volunteers
No
Graduate Endodontic Clinic
Ann Arbor, Michigan, United States
Start Date
October 1, 2012
Primary Completion Date
June 7, 2023
Completion Date
June 7, 2023
Last Updated
July 11, 2023
45
ACTUAL participants
Endodontic Regeneration
PROCEDURE
Lead Sponsor
University of Michigan
NCT03376984
NCT03533231
Data Source & Attribution
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