botulinum toxin treatment in the prior 6 months

history of periocular surgery, brow lift or related procedures

soft tissue augmentation in the lateral canthal region in the prior 12 months

dermabrasion or laser treatment in the periocular region in the last 6 months

topical prescription-strength retinoids in the prior 3 months

present or history of neuromuscular disease

present or history of "dry eye"

systemic aminoglycoside use in the week prior to treatment application

Clinical Trial to Evaluate ANT-1401 in Crow's Feet