rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2

Exclusion Criteria

• •Withdrew from treatment of study Part 1
• •Subjects currently on stimulant, antipsychotic, bupropion or tricyclic antidepressant medications.
• •Prior vagus nerve stimulation (VNS) or electroconvulsive therapy (ECT)
• •Contraindication to MRI
• •Contraindication to rTMS (history of neurological disorder such as seizures, increased intracranial pressure, brain surgery, or head trauma with loss of consciousness for \>15 minutes, history of stroke, family history of epilepsy, intracardiac lines, Anticoagulant, immune suppressive and/or chemotherapy, or those who received any of these therapies within 3 months before enrollment in the study Unstable medication conditions such as hematological or infectious (e.g., human immunodeficiency virus-HIV) disorders, implanted electronic device, metal in the head, or pregnancy)
• •History of schizophrenia, schizoaffective disorder, other \[non mood disorder\] psychosis, depression secondary to a medical condition, mental retardation, substance dependence or abuse within the past year (except nicotine), bipolar disorder, psychotic features in this or previous episodes, amnestic disorder, obsessive compulsive disorder, post-traumatic stress disorder, panic disorder
• •History of autoimmune, endocrine, viral, or vascular disorder.
• •Unstable cardiac disease, uncontrolled hypertension, or sleep apnea
• •Active suicidal intent or plan, or history of attempt within the past 6 months