Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Cereve, Inc.
Age
22–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age \>/= 22
Diagnosis of insomnia that meets criteria for DSM IV diagnosis of primary insomnia and International Classification of Sleep Disorders (ICSD)general insomnia criteria and RDC insomnia disorder criteria
Subjects must remain alcohol-free and avoid drugs that could affect sleep during the study.
\>14 on the Insomnia Severity Index
Sleep -Wake diaries demonstrate sleep efficiency \<85% on at least 50% of nights
You may not be if
Neuropsychiatric disorders that may independently affect sleep, brain function or cognition, such as current major syndromal psychiatric disorders, including DSM-IV mood, anxiety, psychotic, and substance use disorders.
Specific exclusionary diagnoses include major depressive disorder, dysthymic disorder, bipolar disorder, panic disorder, obsessive compulsive disorder, generalized anxiety disorder, any psychotic disorder, and any current substance use disorder.
Unstable medical conditions Raynaud's Disease
Irregular sleep schedules including shift workers;
A latency to persistent sleep \< 15 on either the sleep disorder screening night or the baseline PSG sleep night;
A sleep efficiency \> 85% on either the sleep disorder screening night or the baseline PSG sleep night;
An AHI (apnea hypopnea index) \> 10 and/or a periodic limb movement arousal index (PLMAI) \> 15 from SN1
Body Mass Index \>34
Use of medications known to affect sleep or wake function
Consumption of more than one alcoholic drink per day, or more than 7 drinks per week prior to study entry.
Caffeinated beverages \> 4/day or the equivalent of more than 4 cups of coffee Unable to read or understand English
