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Lead
Shriners Hospitals for Children
Methylnaltrexone will be given to pediatric patients post-operative from spinal fusion surgery on post-operative day number 3 and then again on postoperative day number 4, if no laxation achieved. Various outcome measures, safety and efficacy of the drug will be observed and recorded.
Age
12–21
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
spinal fusion surgery
current opioid use
12 years of age and older
no or inadequate bowel movement by post-operative day 3
You may not be if
known or expected mechanical bowel obstruction
known or suspected lesions of the GI tract
unexpected transfer to ICU
unexpected return to the operating room
patient or parent refusal of methylnaltrexone
incomplete data concerning time to laxation
Clareo Health | Methylnaltrexone Use for Opioid-induced Postoperative Constipation
