Long-term Safety of SPD489 When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia

Exclusion Criteria

• •-Taking lithium, carbamazepine, lamotrigine, gabapentin, cholinesterase inhibitors, modafinil, or other stimulants such as methylphenidate and other amphetamine products
• •Treated with clozapine in past 30 days
• •Lifetime history of stimulant, cocaine, or amphetamine abuse or dependence
• •History of seizures (other than infantile febrile seizures), any tic disorder, or current diagnosis and/or a known family history of Tourette's Disorder, serious neurological disease, history of significant head trauma, dementia, cerebrovascular disease, Parkinson's disease, or intracranial lesions
• •Uncontrolled hypertension
• •History of thyroid disorder that has not been stabilized on thyroid medication
• •Glaucoma
• •Pregnant or nursing
• •Subject has received an investigational product or participated in a clinical study within 30 days