1. Admit to an ICU due to gastrointestinal bleeding AND an INR \> 1.5

2. Patient has chronic liver disease defined as 1 or more of the three following diagnostic criteria:

1. Previous diagnosis of chronic liver disease OR Imaging or biopsy diagnosis of cirrhosis

2. Signs of portal hypertension (ascites, varices, hypersplenism)

3. Laboratory evidence of synthetic dysfunction (INR\>1.5, Bilirubin\> 2.0, Albumin\< 2.5) AND ≥2 physical exam findings on admission associated with chronic liver disease (palmar erythema, spider angiomata, asterixis, caput medusa, gynecomastia)

Predicting Lung Injury From Transfusion in Patients With Liver Disease

What this study is about