Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
With
Danone Global Research & Innovation Center
Age
30–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 30-80 years
Able to provide informed consent and willing to complete follow-up visits.
Estimated glomerular filtration rate between 30 and 60 ml/min/1.73m2
Microalbuminuria \[albumin to creatinine ratio \>2.8 mg/mmol (if female) or \>2.0 mg/mmol if male)\]
You may not be if
Self-reported fluid intake \>10 cups/day or 24-hr urine volume \>3L.
Enrolled in another randomized controlled trial that could influence the intervention, outcomes or data collection of this trial (or previously enrolled in this trial)
Received one or more dialysis treatments in the past month
Kidney transplant recipient (or on waiting list)
Pregnant or breastfeeding
History of kidney stones in past 5 years
Less than two years life expectancy
Serum sodium \<130 mEq/L without suitable explanation
Serum calcium \>2.6 mmol/L without suitable explanation
Currently taking hydrochlorothiazide \>25 mg/d, indapamide \>1.25 mg/d, furosemide \>40 mg, or metolazone \>2.5 mg/d
Currently taking lithium
Patient is under fluid restriction (\< 1.5 L a day or more) for kidney disease, heart failure, or liver disease, AND meets any of the following criteria: i) end stage of the disease (heart left ventricular ejection fraction \<40%, NYHA class 3 or 4, or end stage cirrhosis) or ii) hospitalization secondary to heart failure, ascites and/or anasarca