Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Oslo University Hospital
Background:
When substituting a random biopsy procedure with a few targeted biopsies, it is of outmost importance to know immediately if the biopsy is positive or not. A recent study has demonstrated a high sensitivity and specificity of imprint cytology of random biopsies.
Aim:
The correlation between cytological imprints and histology of targeted prostate biopsies
Material\&Method:
All patients in this study are already participating in an ongoing randomized biopsy study (NCT01455792) comparing:
1. Preoperative MRI and targeted biopsies + random biopsies .
2. Random biopsies (gold standard).
Only patients with a positive MRI were included in this collateral study.
The cytological imprints (negative/positive) of each targeted biopsy is compared to the histology (negative/positive) and Gleason score.
Age
Any age
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Prostate specific antigene (PSA) 4-20ng/ml, and/or abnormal digital rectal examination
No previous prostate biopsies
Positive MRI
Signed letter of informed concent
You may not be if
Contraindications to MRI
Previous prostate biopsies
Clareo Health | Clinical Study Evaluating Targeted Biopsies and Cytological Imprints in Prostate Cancer
