Vitamin D for Women at Increased Risk of Developing Ovarian, Fallopian, or Primary Peritoneal Cancer

You may be eligible if

• Patients must be undergoing prophylactic or therapeutic oophorectomy
• Patients must be considered to be at a high risk of developing ovarian, fallopian or primary peritoneal cancer, according to 1 or more of the following characteristics:
• Patients with a BRCA mutation including variants of uncertain significance
• Patients with Lynch syndrome
• Patients with a family history that places them at high risk of developing ovarian cancer
• Patients with a personal history of breast cancer
• Patients must be women age 18 and older
• Patients who are of childbearing potential and sexually active must use contraception while on study.
• Patients must have a signed and witnessed informed consent and authorization permitting release of personal health information prior to registration on the study.
• Hypercalcemia (\>11.5mg/dL)
• Hypervitaminosis D
• Malabsorption syndrome
• Active gallbladder disease
• Active hepatic disease
• Hypoparathyroidism
• Leukemia
• Nephrolithiasis
• Renal failure sarcoidosis
• Renal disease (eGFR\<59 ml/min/1.73m2)