Vitamin D for Women at Increased Risk of Developing Ovarian, Fallopian, or Primary Peritoneal Cancer

Inclusion Criteria

• •Patients must be undergoing prophylactic or therapeutic oophorectomy
• •Patients must be considered to be at a high risk of developing ovarian, fallopian or primary peritoneal cancer, according to 1 or more of the following characteristics:
• •Patients with a BRCA mutation including variants of uncertain significance
• •Patients with Lynch syndrome
• •Patients with a family history that places them at high risk of developing ovarian cancer
• •Patients with a personal history of breast cancer
• •Patients must be women age 18 and older
• •Patients who are of childbearing potential and sexually active must use contraception while on study.
• •Patients must have a signed and witnessed informed consent and authorization permitting release of personal health information prior to registration on the study.
• •Hypercalcemia (\>11.5mg/dL)
• •Hypervitaminosis D
• •Malabsorption syndrome
• •Active gallbladder disease
• •Active hepatic disease
• •Hypoparathyroidism
• •Leukemia
• •Nephrolithiasis
• •Renal failure sarcoidosis
• •Renal disease (eGFR\<59 ml/min/1.73m2)