Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Wuerzburg University Hospital
Age
12–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Confirmed diagnosis of Cystic Fibrosis
Age ≥12 years
Forced expiratory volume in 1 second (FEV1) ≥ 35% predicted
Access to the internet
You may not be if
Participation in another clinical trial up to 4 weeks prior to the first baseline visit
Pregnancy/Breastfeeding
Inability to exercise
More than 4 hours of reported strenuous physical activities per week currently or up to 3 months prior to baseline measurements and not already planned within the coming 6 months.
Unstable condition precluding exercise (major hemoptysis or pneumothorax within the last 3 months, acute exacerbation and iv-antibiotics during the last 4 weeks, planned surgery, listed for lung transplantation, major musculoskeletal injuries such as fractures or sprains during the last 2 months, others according to the impression of the doctor)
Cardiac arrhythmias with exercise
Requiring additional oxygen with exercise
Recent diagnosis of diabetes 3 months prior to screening or at screening
Recent changes in medication 1 month or less prior to screening (systemic steroids, ibuprofen, inhaled antibiotics, mannitol, DNAse, hypertonic saline)
At least one G551D mutation and not on ivacaftor (VX770) yet but planned start or planned stop of ivacaftor during the trial
