Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Texas Southwestern Medical Center
With
AstraZeneca
Age
18–74
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Undergoing clinically-indicated PCI for stable or progressive exertional angina without rest angina, ST-segment shift, or elevated CK-MB or troponin-T or I
Willing and able to give informed consent and to comply with study procedures
Found to have single or two-vessel obstructive, non-occlusive (≥ 70% but \< 100% stenosis), coronary artery disease with plans for treatment of all lesions by PCI
Target lesion location in the proximal or mid coronary vessel with reference diameter ≥ 2.5 mm
You may not be if
Known allergy to aspirin, clopidogrel, or ticagrelor
Need for concomitant cardiac procedure, such as valve repair or replacement
Age ≥ 75
Concomitant theophylline/aminophylline use
Baseline ECG with infarct or conduction abnormalities (i.e. LVH with repolarization abnormality, bundle branch block, ST-segment abnormalities)
Presenting with an ST-segment elevation or non ST-segment elevation myocardial infarction
Evidence of prior myocardial infarction by cardiac imaging
Depressed left ventricular systolic function (ejection fraction \< 50%)
Clinical congestive heart failure
End-stage renal disease
Presence of coronary collaterals on diagnostic coronary angiography
Presence of coronary thrombus on diagnostic coronary angiography
Diffuse obstructive disease (≥ 70% stenosis) in the distal segment of the target vessel
Left main and/or three-vessel coronary artery disease
