Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
AbbVie (prior sponsor, Abbott)
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Has a primary Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition-Text Revision diagnosis of major depressive disorder without psychotic features
No current antidepressant treatment within 7 half-lives or 2 weeks, whichever is longer, prior to Day minus 1.
Can safely be treated on an outpatient basis.
A condition of general good physical health.
Surgically sterile, using a highly effective method of birth control or (if female) at least 1 year post menopausal.
You may not be if
History of hypersensitivity, intolerance or adverse reaction to escitalopram that led to discontinuation, or hypersensitivity to citalopram. History of serotonin syndrome.
Inadequate response to more than two different antidepressant medications during the current major depressive episode.
History of electroconvulsive therapy, vagal nerve stimulation or deep brain stimulation.
History of transcranial magnetic stimulation during the current major depressive episode.
Psychotherapy that has not been ongoing for at least 3 months prior to Day minus 1.
