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COMPLETEDNANCT01740921

GLP-1 and Microvascular Function in Type 2 Diabetes

Some gut hormones, called incretins, stimulate insulin production in order to control sugar levels but also activate brain centres and signal to stop eating. Current administration of incretin-based t...

Lead sponsor: Royal Devon and Exeter NHS Foundation Trust•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Royal Devon and Exeter NHS Foundation Trust

Collaborators

University of Exeter

Age

18 - 70 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Type 2 diabetes and an HbA1C between 7-8.5% on a stable dose of sulphonylurea and/or metformin

Exclusion Criteria

•use of insulin
•corticosteroids
•contraceptives, tamoxifen
•methotrexate
•DPP-IV inhibitors
•pregnancy
•lactation
•endocrine disorders
•acute MI or cerebrovascular disease
•Raynaud's disease or connective tissue disease
•current or previous history of malignancy
•subjects treated with ergotamine derivatives
•unstable blood pressure for the last 3 months
•current treatment with warfarin
•subjects on any anti-inflammatory or anti-platelet agents
•history of any bleeding disorders and GI bleeds.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 17, 2017Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment39

Start dateJan 2011

Last updatedFeb 17, 2017

Condition

Type 2 Diabetes

Locations shown

Peninsula Clinical Research Facility

Exeter

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 17, 2017Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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