Lead Sponsor

University of California, Los Angeles

Age

21 - 65 years

Sex

ALL

Healthy Volunteers

No

•1. Active stage TO as determined by symptom onset of under 9 months.
•2. Upper eyelid retraction of 1mm or greater in one or both eyes.
•3. Complaints of either significant ocular symptoms (despite appropriate use of ocular lubricants), or cosmetic deformity associated with the eyelid retraction.

•1. Age less than 21 years: due to lack of data on safety for HAG fillers in pediatric population
•2. Age over 65 years of age: as HAG filler effect may be different in this population
•3. Are pregnant or nursing: as there is little safety data on potential teratogenicity of HAG fillers
•4. Have a demonstrated allergy to HAG fillers or lidocaine
•5. Have a current infection, skin sore, pimple, rash, hive or cyst over the injection site: to avoid worsening the infection or transmitting it
•6. Have a bleeding disorder or currently taking blood thinning medications such as Coumadin, heparin or acetylsalicylic acid on a daily basis.

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