Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
OPKO Health, Inc.
With
Elan Pharmaceuticals
Age
50–95
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of Probable AD according to the National Institute on Aging- Alzheimer's Association (NIA-AA) guidelines (McKhann et al 2011).
MMSE score of 5 to 24 (inclusive) at the Screening Visit.
Has clinically significant agitation/aggression defined as Neuropsychiatric Inventory (NPI)-agitation/aggression subscore of ≥4.
No response or suboptimal response to standard nonpharmacological interventions.
You may not be if
The agitation/aggression is attributable to concomitant medications, environmental conditions, or active medical or psychiatric condition.
Current diagnosis of major depressive disorder according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition Text Revision (DSM IV TR).
Has persistent and distressing psychotic symptoms (delusion and/or hallucinations) that require psychiatric hospitalization.
Clareo Health | Efficacy and Safety Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease
