Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Henry Ford Health System
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Aged 18 years or older
Receiving intravenous vancomycin for the treatment of healthcare associated pneumonia, osteomyelitis/septic arthritis, endocarditis/bacteremia, or acute bacterial skin and skin structure infections
Expected to receive vancomycin for at least 72 hours and are within the first 72 hours of therapy
Have at least two or more of the following risk factors for drug-induced nephrotoxicity: a) receipt high-dose vancomycin therapy (greater than or equal to four grams per day) b) receipt of vasopressors c) receipt of nephrotoxic drugs (i.e. aminoglycosides, furosemide, acyclovir, amphotericin b, colistin, and intravenous contrast dye) d) pre-existing renal dysfunction (i.e. SCr greater than or equal to 1.5 mg/dL).
You may not be if
Pregnancy
End-stage renal disease
Receipt of more than 4 grams of vancomycin prior to enrollment on current admission
Absolute neutrophil count \< 1000/mm3
Clareo Health | Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients