Willing to abstain from cannabis use for four weeks
For schizophrenia:
Meets DSM-IV-TR criteria for schizophrenia or schizoaffective disorder
For prodrome for psychotic illness:
Meets SIPS criteria for prodromal syndrome
For family history positive:
First degree relative with alcoholism
For Post-Traumatic Stress Disorder
Meets DSM-IV-TR criteria for PTSD
For OUD
Meets DSM-IV-TR criteria for Opioid Use Disorder
You may not be if
Current neuro-psychiatric illness (including cannabis dependence) or severe systemic disease. Cannabis use disorder is permitted in the cannabis dependent group. Schizophrenia and schizoaffective disorder is permitted in the schizophrenia group. Psychotic symptoms are permitted in the prodromal group. Post-Traumatic Stress Disorder is permitted in the PTSD group and Opioid Use Disorder is permitted in the OUD group.
Presence of ferromagnetic metal in the body or heart pacemaker
Have had exposure to ionizing radiation that in combination with the study tracer would result in a cumulative exposure that exceeds recommended exposure limits
