Role of Ipsilateral Motor Cortex in Executing Movements With Increasing Demand on Precision

You may be eligible if

• Age 18-80
• Single cerebral ischemic infarction one month prior to entering study
• Affecting only one hemisphere as defined by MRI of the brain
• At the time of cerebral infarct a motor deficit of hand of Medical Research Council Scale for Muscle Strength (MRC) of \< 4- of wrist and finger extension/flexion movement
• Fugl Meyer score \> 27/66 (motor domain, upper extremity)
• Ability to operate joystick at largest target level
• No other neurological disorder
• No intake of Central Nervous System (CNS) active drugs
• Ability to give informed consent
• Ability to meet criteria of inclusion experiment
• No major cognitive impairment
• Age 55-80 years with no neurological or psychiatric diseases
• Normal neurological examination
• Normal MRI of the brain
• Normal neuropsychological testing
• No intake of CNS active drugs that interfere with data collection
• No contraindication to TMS
• Ability to give informed consent