A Phase II Trial of PG2 in Patients With Advanced Pharyngeal or Laryngeal Squamous Cell Carcinoma Under Concurrent Chemoradiotherapy

Inclusion Criteria

• •Histological confirmation of squamous cell carcinoma
• •Primary tumor site in the head and neck area
• •Stage III or IV disease
• •Measurable locoregional disease and no distant metastasis
• •No prior cancer treatment
• •20-70 years old
• •KPS ≧ 70
• •Adequate bone marrow, liver, and renal function
• •Fed with gastric tubes but without intestinal malabsorption or obstruction
• •Not pregnancy and use a reliable contraceptive method during the study
• •Signed informed consent
• •Willing and able to complete quality of life questionnaires