Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Louisville
With
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Data will be collected from 120 subjects undergoing hemodialysis treatment at 3 clinical sites across United States (40 per site).5.5 mL blood specimen will be drawn during midweek treatment (Wed/Thu) to measure:
Hemoglobin Concentration Hematocrit Red Blood Cell Count Platelet Count Reticulocyte Percentage Reticulocyte Hemoglobin Mean Cellular Hemoglobin Mean Cellular Hemoglobin Concentration Mean Cell Volume Red Cell Volume Distribution Width Mean Platelet Volume Serum Iron Serum Ferritin Transferrin Saturation Hepcidin Soluble Transferrin Receptor
Weekly ESA and Iron dose delivered will also be recorded.
From these data:
1. a mathematical model will be established to find biomarkers most descriptive with respect to erythropoiesis-iron synergy,
2. a mathematical model will be established to correlate iron dose with iron markers.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
receiving or expected to receive ESA
You may not be if
life expectancy less than 12 months
frequent (once or more per month w/in last 6 months) uncontrolled blood loss
frequent (once or more per month w/in last 6 months) hospitalization
frequent (once or more per month w/in last 6 months) access complications
