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Lead
Washington University School of Medicine
Diffusion tensor imaging (DTI) parameters will correlate with severity of spinal cord injury in SCI patients as seen in rodent models. We will test whether the quantitative decrease in axial (λ║) diffusivity (a biomarker of axonal injury), will predict long-term functional outcomes for patients with a SCI.
Specific Aim: To examine patients after an acute SCI using DTI and to correlate the extent of acute decrease in λ║ with the presenting ASIA motor score and long-term functional outcome of the patient.
Age
18–65
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
18-65 years of age
Cervical spinal cord injury
physically and mentally willing to comply with imaging
lives in immediate area with no plans to relocate
You may not be if
Associated moderate to severe head injury
Active malignancy
Previous spinal cord injury
pregnancy
inability to tolerate MRI scanning
Clareo Health | Diffusion Tensor Imaging to Assess the Functional Outcomes of Adults With Cervical Spinal Cord Injuries