The Effect of Administration of Low Dose Adrenaline During Surgery on Bleeding During Hip Surgery

Exclusion Criteria

• •Allergy towards adrenaline
• •Current treatment with: ADP receptor inhibitors or Vitamin K antagonists (within 5 days), Factor Xa inhibitors or Thrombin inhibitors (within 1 day), heparin (excluding low molecular weight heparin for perioperative thromboprophylaxis).
• •Current treatment with tricyclic antidepressants
• •Use of MAO inhibitors (within previous 14 days) or COMT inhibitors (within 2 days).
• •Acute coronary syndrome / myocardial infarction within the previous 6 months.
• •not willing to accept blood transfusion
• •Participation in other clinical trial within previous 30 days
• •Women of childbearing age (without menopause for at least 12 months)
• •Glaucoma
• •Pheochromocytoma
• •Low serum K+ (\< 3.0 mmol/L)
• •Thyrotoxicosis
• •Digoxin intoxication
• •Alcohol og drug abuse (investigators judgement)