Histologically or cytologically confirmed stage IIIB/IV lung cancer(exclude patients confirmed by sputum cytology)
No previous targeted treatment such as gefitinib, erlotinib.
With a measurable disease(longest diameters \>=10mm with Spiral computed tomography (CT)and \>=20mm with conventional CT) according to RECIST Criteria
WHO performance status(PS)\<= 2
N\>=1.5×109/L, Plt\>=1.0×109/L,Hb\>=10g/dL;AST\&ALT should \<3ULN(without liver metastasis) or \<5ULN(with liver metastasis).TBIL\<=1.5ULN.
Signed and dated informed consent before the start of specific protocol procedures.
You may not be if
Allergic to icotinib
Patients with metastatic brain tumors with symptoms.
Experience of Anti-EGFR(the epidermal growth factor receptor) Monoclonal Antibody or small molecular compounds therapy such as gefitinib, erlotinib or Cetuximab.
Severe systemic disease out of control such as unstable or uncompensated respiratory,cardiac,liver,renal diseases.
Clareo Health | Icotinib in Combination With Chemotherapy Versus Chemotherapy Alone in Patients Progressed After Icotinib Treatment
