Effect of the Consumption of a Probiotic Strain on the Prevention of Post-operative Recurrence in Crohn's Disease

Exclusion Criteria

• •One or more intestinal resection during the 5 last years before the last surgery
• •Presence of any severe additional disease
• •For female patient : pregnancy or breast feeding
• •For pre-menopausal female patient : no effective contraceptive methods used (combined oestrogen-progestogen pill or Intrauterine Device)
• •Patient currently in an exclusion period following participation in another clinical trial
• •Patient in a situation which in the investigator's opinion could interfere with optimal participation in the present study or could constitute a special risk for the patient
• •Significant presence of Crohn's disease in other intestinal tracts
• •Small bowel cumulative resection exceeding 1 meter
• •Patient with ileostomy
• •Subtotal colectomy with ileo-rectal anastomosis
• •Severe post-operative septic complications (fistula, peritonitis), leading to administration of more than 15 days of post-operative antibiotherapy)
• •Intake of unauthorised treatments (mesalazine, olsalazine or sulfasalazine, 5-Aminosalicylates (5-ASA) or 4-Aminosalicylates (4-ASA)) ; corticoïds and immunosuppressors) after surgery except corticoids which will have to be stopped within 6 weeks after surgery according to standardised stepwise dose reductions
• •Patient under artificial nutrition
• •Subject with a loss of personal liberty, by administrative or judicial decision, or major with a legal guardian