History of serious or unexpected reaction to fluoropyrimidine therapy

Hypersensitivity to the active ingredient of Xeloda or to any of the excipients of the product, or to fluorouracil

Known dihydropyrimidine dehydrogenase deficiency

Pregnancy or lactation

Inadequate bone marrow, hepatic or renal function

Treatment with sorivudine or its chemical analogues (for example, brivudine)

If any contraindication for any drug used in the combination treatment schedules is present, the drug in question cannot be used

An Observational Study of First-Line Capecitabine Based Chemotherapy in Participants With Metastatic Colorectal Cancer