Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Central Hospital, Nancy, France
Age
65–90
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
All subjects (groups A and B):
able to walk autonomously, that is without help, whether human or technical, except for a walking cane
are aged 65 to 90 years
have never been in the "art, memory and life" garden at the Paul SPILLMANN Centre prior to the study
have given their written consent after receiving clear and intelligible oral and written information.
Group A : patients with Alzheimer's disease:
diagnosis of probable Alzheimer's disease according to NINCDS-ADRDA diagnostic criteria (Mc KHANN et al., 1984)
score less than or equal to 4 on the Hachinski ischemic scale (Hachinski et al., 1984)
Folstein MMSE score between 10 and 24 inclusively
score equal to 5 or 6 on the Reisberg Global Deterioration Scale (REISBERG et al., 1982).
stable, specific treatment of Alzheimer's disease (cholinesterase and memantine)
taking of psychotropic drugs authorized, but no change in treatment during at least the last 48 hours
Group B: healthy control subjects:
absence of dementia according to NINCDS-ADRDA criteria (Mc KHANN et al., 1984)
normal performance on Folstein MMSE, according to the GRECO (en français : Groupe de REflexions sur les Evaluations Cognitives) standards (Reflection Group on Cognitive Assessments)
You may not be if
For all subjects (groups A and B):
Absence of social security coverage
sensory deficit interfering with the task
aphasia interfering with the task
history of head trauma (with loss of consciousness)
chronic alcoholism
refusal or inability to obtain written informed consent form from the patient
legally protected person
severe depression: score higher than 20 on the 30-item Geriatric Depression Scale (GDS)
Group A : patients with Alzheimer's disease:
other neurological or psychiatric diseases that may affect the assessment Group B: healthy control subjects
neurological or psychiatric diseases that may affect the assessment
