Oral Propionate to Treat and Prevent Diabetes

Exclusion Criteria

• •* Gained or lost ≥ 3kg weight in the past three months
• •* Taken prescription medicines having an impact on metabolism, appetite regulation, glucose homeostasis and hormonal regulation
• •* Taken any dietary supplements in the last 6 months
• •* Any chronic illness
• •* Cardiovascular disease
• •* Excess alcohol intake
• •* Current smokers
• •* Any gastrointestinal disorder e.g. Crohn's disease, coeliac disease or irritable bowel syndrome
• •* A history of drug or alcohol abuse in the last 2 years
• •* Pregnancy (all women of child bearing age will undergo a pregnancy test).
• •* Pancreatitis
• •* Use of medications likely to interfere with glucose metabolism, appetite regulation, hormonal balance.