Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
With
Solving Kids' Cancer
Delivering the chemotherapeutic agent directly to the tumor via the arterial system avoids the complications and adverse events associated with toxicity from systemic chemotherapy.
Age
0–17
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Pediatric patients of all ages with progressive DIPG.
Consensus following presentation of the case at the multidisciplinary Pediatric Neuro-Oncology conference, which includes participation of neuro-oncology, neurosurgery, radiation oncology, interventional neuroradiology and neurology.
You may not be if
Documented hypercoagulable disorders or vasculopathies
* INR value more than a Grade 1 toxicity by CTCAE v 4.0 criteria (\>1 - 1.5 x ULN; \>1 - 1.5 times above baseline if on anticoagulation).
* APTT value more than a Grade 1 toxicity by CTCAE v 4.0 criteria (\>ULN - 1.5 x ULN).
Platelets less than 50 x 103/mm3
Absolute neutrophil count less than 500/ mm3
Pregnancy
Documented severe allergic reaction to IV iodinated contrast, specifically bronchospasm and anaphylaxis.
