A Study to Test Safety and Efficacy of Baricitinib in Participants With Diabetic Kidney Disease

Exclusion Criteria

• •Too high blood pressure when you enter the study
• •Some specific medicines used to treat high blood pressure or diabetic kidney disease
• •Frequent high blood glucose levels
• •Renal transplant or past history of dialysis
• •Nonsteroidal anti-inflammatory drugs (NSAIDs)
• •Had a special X-ray in the past 30 days which involved also receiving an injection of dye into the vein
• •Major surgery within 8 weeks of study entry or will require major surgery during the study
• •Some types of vaccination
• •Shingles or currently have symptoms of a cold sore
• •Serious viral, bacterial, fungal, or parasitic infection, or a urinary infection, Tuberculosis (TB)
• •Human immunodeficiency virus (HIV) infection- the virus that causes Acquired immunodeficiency syndrome (AIDS)
• •Have or had some blood disorders, enlarged lymph glands or spleen, or some cancers.
• •Serious circulatory, breathing, liver, stomach or bowel problems, neurological or psychiatric disorders
• •Heart attack or heart failure, or a stroke
• •Other serious disorders or illnesses
• •Electrocardiogram (ECG) heart trace abnormalities
• •Alcohol or illegal drug abuse
• •Donated more than 500 mL of blood in the last 30 days (no blood donations allowed during the study)
• •Pregnant or breastfeeding