Randomized Cohort: Requires CABG surgery with a SVG to the right coronary artery (RCA) system AND the left circumflex artery (LCX) system with a ≥ 70% stenosis in each of the two systems.
Single Vessel Cohort: Requires CABG surgery with a SVG to the RCA system or the LCX system with a \> 70% stenosis in the system.
Medial sternotomy with cardiopulmonary bypass (CPB) during surgery.
Both saphenous vein graft length are adequate for planned intervention, vein outer diameter is between 3.6 mm and 7.0 mm and double wall thickness less than 1.4 mm.
Agreement to post-procedure follow-up contact and testing (including follow-up coronary angiogram).
You may not be if
Concomitant non-CABG cardiac procedure.
Prior cardiac surgery (does not include percutaneous procedures).
Cerebrovascular or transient ischemia attack within 30 days of the CABG procedure.
Age \> 85 years.
Left ventricular ejection fraction ≤ 35%.
Creatinine \> 133 μmol/L (1.5 mg/dL) prior to CABG procedure or on chronic dialysis.
STEMI within 7 days or total CK \> 2 times the upper limit of normal prior to the CABG procedure.
Both enrolled grafts will feed non-viable myocardial territory.
Diffuse atherosclerotic disease (\> 70%) distal to either of the enrolled target coronary arteries.
Randomized Cohort: By visual estimate, the target coronary artery diameter of both the right coronary system and left circumflex system must be within 1.5mm of each other.
Planned endarterectomy of the target coronary artery.