1. Known contraindications or sensitivities to study medication or its components

2. Any ocular condition that, in the opinion of the investigator, could affect the subject's safety or trial parameters

3. Use of disallowed medication during the period indicated prior to the enrollment or during the study

4. Be a female who is currently pregnant, planning a pregnancy, lactating, or not using a medically acceptable form of birth control

A Study of RX-10045 in the Treatment of Dry Eye Disease