Microwave Treatment and Corneal Collagen Crosslinking for Keratoconus

Exclusion Criteria

• •Contraindications, sensitivity or known allergy to the use of the test articles(S) or their components
• •If female, be pregnant, nursing, or planning a pregnancy or have a positive urine pregnancy test at Visit 2 prior to treatment or during the course of the study
• •Eyes classified as either normal,atypical normal,keratoconus suspect or mild keratoconus on the severity grading scheme
• •A history of the insertion of INTACS in the eye to be treated
• •A history of previous limbal relaxing incision procedure in the eye to be treated
• •Corneal pachymetry that is \<350 microns at the thinnest point measured by Pentacam in the eye to be treated
• •Eyes which are aphakic
• •Eyes which are pseudophakic and do not have a UV blocking lens implanted
• •Previous ocular condition (other than refractive error) in the eye to be treated that may predispose the eye for future complications.
• •A history of delayed epithelial healing in the eye to be treated
• •Patients with nystagmus or any other condition that would prevent a steady gaze during the treatment or other diagnostic tests
• •Patients with a current condition that, in the investigator's opinion,would interfere with or prolong epithelial healing
• •Taking Vitamin C (ascorbic acid) supplements within 1 week of the cross-linking treatment
• •A history of previous corneal cross-linking treatment in the eye to be treated
• •Have used an investigational drug or device within 30 days of the study or be concurrently enrolled in another investigational drug or device study within 30 days of the study