3-Tesla MRI in Finding Tumors in Patients With Known or Suspected Prostate Cancer

PRIMARY OBJECTIVES: I. To assess the impact of prostate MRI, without an endorectal coil, done at 3-Tesla on surgical management. This would be performed by examining the agreement of lesion location based on the MRI compared to the lesion location based on pathology and/or surgery and local extent of the disease, i.e. involvement of contiguous organs and local lymph nodes, based on the MRI compared to the local extent based on pathology and/or surgery. II. To test the reproducibility of functional MRI (dynamic-contrast enhanced \[DCE\_MRI\] MRI, magnetic resonance \[MR\] spectroscopy and diffusion-weighted MRI). SECONDARY OBJECTIVES: I. To assess the usefulness of MRI data in treatment planning for radiation therapy, and to test the feasibility of amide-proton-transfer MRI in prostate cancer detection. II. To evaluate MRI changes in prostate and tumor morphology between endorectal coil versus no endorectal coil. III. To assess the usefulness of ex-vivo prostate specimen MRI for accurate co-registration between in-vivo MRI of the prostate and pathology slides. OUTLINE: Patients undergo 3-tesla (3T) MRI, including DCE-MRI, diffusion-weighted MRI, amide-proton-transfer MRI, and MR spectroscopy scans. Patients may undergo an additional 3T MRI scan at least 24 hours after the initial scan.