Male or non-pregnant, non-lactating female patients

Diagnosis of moderate to severe AS with prior documented radiologic evidence (x-ray) fulfilling the Modified New York criteria for AS (1984)

Patients should have been on NSAIDs with an inadequate response

Patients who were regularly taking NSAIDs as part of their AS therapy are required to be on a stable dose

Patients who had been on an anti-TNFα agent (not more than one) must have experienced an inadequate response

16 Week Efficacy and 5 Year Long Term Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Ankylosing Spondylitis