Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Washington University School of Medicine
Subjects studied on four occasions:
1. Intravenous buprenorphine
2. Sublingual buprenorphine
3. Cyclosporine, then intravenous buprenorphine. Subjects then take oral cyclosporine twice daily, until
4. Sublingual buprenorphine; continue oral cyclosporine twice daily for 5 days
Age
18–50
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
18-50 yr old
Good general health with no remarkable medical conditions
BMI \< 33
Provide informed consent
You may not be if
Known history of liver or kidney disease
Use of prescription or non prescription medications, herbals or foods known to be metabolized by or affecting CYP3A
Females who are pregnant or nursing
Known history of drug or alcohol addiction (prior or present addiction or treatment for addiction)
Direct physical access to and routine handling of addicting drugs in the regular course of duty (a routine exclusion from studies of drugs with addiction potential)
Clareo Health | Buprenorphine Disposition and Cyclosporine
