Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Penumbra Inc.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
At least 18 years old
A wide-neck intracranial saccular aneurysm with a neck ≥ 4mm or a dome to neck ratio \<2 in the ICA from the cavernous segment to the carotid terminus (including the paraclinoid, ophthalmic, hypophyseal and posterior communicating segments)
Life expectancy \> 12 months
Signed Informed Consent
You may not be if
Females who are pregnant or intend to become pregnant during the study. (Females of child-bearing potential must have a urinary pregnancy test within 7 days of enrollment)
Extradural aneurysms
Known multiple untreated cerebral aneurysms at study entry
Recent history of subarachnoid hemorrhage, intracranial hemorrhage, or major surgery within one month of enrollment
Admission platelet \<50,000 or any known hemorrhagic diathesis, coagulation deficiency, or on oral anticoagulant therapy with an INR \>3.0
Contraindication to angiography such as elevated creatinine or known allergy to angiographic contrast
Contraindication to CT and/or MRI scans
Known allergy to the metal component of the Penumbra Liberty Stent System
Evidence of active infection (WBC \>10x109 /L)
Any medical conditions that will not allow the necessary follow-up for this study (e.g., pre-existing neurological or psychiatric diseases)
Current substance-abuse /illicit drug use
Angiographic evidence of an arterial stenosis proximal to the target lesion that could prevent device deployment
Contraindications to study medications (heparin, aspirin, clopidogrel, and radiographic contrasts)
Clareo Health | The Penumbra Liberty Trial: Safety and Effectiveness in the Treatment of Wide-Neck Intracranial Aneurysms
