Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris

Exclusion Criteria

• •Dermatological condition of face or facial hair that could interfere with clinical evaluations subjects who have used the following medications (topical refers only to the facial area) will not be eligible:
• •Within 1 week prior to randomization:
• •Medicated facial cleansers
• •Topical acne treatments (other than those listed below)
• •Within 4 weeks prior to randomization:
• •Topical retinoids
• •Topical anti-inflammatories and corticosteroids
• •Systemic antibiotics
• •Systemic acne treatments
• •Within 12 weeks prior to randomization:
• •Systemic retinoids
• •Systemic corticosteroids
• •Pseudomembranous colitis or antibiotic-associated colitis
• •Hepatitis, liver damage or renal impairment