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The purpose of the study is to investigate if serological parameters such as "extracellular Serum-Tryptase (ST)" and "eosinophilic cationic protein (ECP)" are useful for the diagnosis and surveillance of the eosinophilic esophagitis (EE).
The eosinophilic esophagitis (EE) is chronic inflammatory and immunological disease. The diagnosis of EE is based upon large numbers of eosinophils in the esophagus on histopathologic examination (\> 20 eosinophils per high powered field in at least one specimen) despite acid suppression with a Proton-Pump-Inhibitor (PPI) for at least two weeks. There are no diagnostic serological markers for EE so far, so that the purpose of the study is to investigate serological markers which are established in other allergic diseases.
Age
18 - 80 years
Sex
ALL
Healthy Volunteers
No
II. Medical Department, Technical University Munich
Munich, Bavaria, Germany
Start Date
January 1, 2011
Primary Completion Date
October 1, 2012
Last Updated
January 9, 2025
20
ESTIMATED participants
Fluticasone
DRUG
Lead Sponsor
Technical University of Munich
NCT06693531
NCT05199532
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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View ClinicalTrials.gov Terms and ConditionsNCT06596252