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Keep this study
Lead
University of Sao Paulo
Overview
The present study is a double-blind randomized clinical trial in which patients should be allocated from a General Psychiatry Service into two groups (tDCS-active x tDCS-sham). Subjects who fulfilled eligibility criteria will undergo ten days of consecutive stimulation (active or sham) and will return after two to four weeks for final clinical assessment. Patients who shown no response in rating scales and that were allocated to sham intervention group will be able to choose whether or not they want to undergo the active intervention at follow up (partial cross-over)
Age
18–59
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
patients with age between 18-59 years
diagnostic of Schizophrenia or Schizoaffective Disorder as stated by DSM-IV and confirmed by SCID (Structured Clinical Interview for DSMIV), to be tested by a psychiatrist
baseline score higher than 20 for negative symptoms at PAAN
patients able to read and understand Portuguese.
You may not be if
other psychiatric diagnosis
criteria for bipolar disorder; dementia; other psychotic disturbs; substance related disorders
presence of other severe neurological or clinical diseases
presence of suicidal behavior (planning or attempt in the previous 4 weeks)
pregnancy
incapacity of coping with the informed consent
specific tDCS limitations (such as anatomic problems)
Regarding medication: all patients should have stable dosology of medications for at least 6 weeks
Clareo Health | Transcranial Direct Current Stimulation (tDCS) as Therapeutical Strategy for Negative Symptoms in Schizophrenia